Smilax zeylanica: A Promising Antilipidemix and Antiobesity Agent

Background: It is well established fact that obesity has now said to be a disease status.The phytochemicals have always been looked for their enormous stored potential. Similax zeylanica is a naturally occurring flavonoid known for its pharmacological potential. In this study it was aimed to determine the antiobesity and antilipidemic effect of various Similax zeylanica extract.

Materials and Methods: The pharmacological screening of Cyclohexane extract of Smilax zeylanica (SZH), ethyl acetate extract Smilax zeylanica (SZE) and methanolic extract of Smilax zeylanica (SZM) was performed. The acute toxicity studies were performed on various animal groups. Obesity was diet induced.The plasma samples were investigated for various biochemical parameters such as glucose, lipid profile (Cholesterol, TG, HDL, LDL and VLDL), Liver function test (SGPT, SGOT).

Results and Conclusion: The various parameters studied showed that the methanolic extracts of Similax zeylanica showed enormous antiobesity potential and concluded for the supplementation for antilipidemic effect.