Elhasan, Mogahid Mahmoud and Kheir, Omer Osman and Patwa, Yashwi Haresh and Bakhit, Aya Tarig and Abdalla, Hala Ibrahim (2022) TREAT-B has Good Accuracy in Selecting HBV Infected Patients for Treatment in Sudan. Asian Journal of Medicine and Health, 20 (12). pp. 204-211. ISSN 2456-8414
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Abstract
Non-invasive and invasive diagnostic methods, which are not readily available in Sudan, are used to guide HBV treatment. Africa adopted the TREAT-B as a straightforward score in 2018 to identify patients in need of anti-HBV treatment.
Objective: To compare the diagnostic accuracy of the TREAT-B score to the standard scores EASL and AASLD in HBV patients.
Methods: At Ibn Sina Specialized Hospital, 108 HBV patients were enrolled in an analytical cross-sectional study (January- October 2019). Data was collected using an interviewer-administered questionnaire and analyzed using SPSS.
Results: Eight patients (7.4%) were eligible for therapy under the AASLD recommendations, 18 patients (16.7%) were suitable under the EASL guidelines, and twenty-seven patients (25%) were eligible under the TREAT-B guidelines. According to the Wald statistic, the AUROC of TREAT-B (0.883; 95% CI 0.790-0.976; Sen. 85.3%; Sp. 70.3%) was substantially higher than the AUROC of the AASLD criteria (0.722; 95% CI 0. 0.566-0.878; Sen. 74.4%; Sp. 69.8%); and lower than the AUROC of the EASL criteria (0.952; 95% CI 0.790-0.976.
Conclusion: The TREAT-B score was effective at identifying HBV-infected patients who should receive antiviral treatment.
Item Type: | Article |
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Subjects: | European Repository > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 10 Jan 2023 06:55 |
Last Modified: | 31 Jan 2024 03:52 |
URI: | http://go7publish.com/id/eprint/1821 |