EVALUATION OF In Vitro ANTI-INFLAMMATORY ACTIVITY OF FRESHWATER SNAIL

Animal derived natural products contributed a major part in traditional medicine to prevent inflammation related diseases. The majority of clinically important medicines belong to steroidal or non-steroidal anti-inflammatory chemical therapeutic for the treatment of various inflammatory diseases and has severe side effects. Molluscs are rich in biologically active natural products that provide new potential sources of anti-inflammatory agents. The present study investigates the anti-inflammatory activity of freshwater snail (Pila globosa) through various in vitro models. Results of the present study concluded that snail shows potential anti-inflammatory activity was observed in a dose-dependent manner. The anti-inflammatory activity in higher doses (500mg/ml) of snail homogenate was similar to standard drug as Diclofenac sodium. This study is the scientific report that provides the convincing anti-inflammatory activity of snail evidence for scientific validity to its traditionally used by the local populace of south India.