Akhiani, Ali A. and Martner, Anna (2022) Role of Phosphoinositide 3-Kinase in Regulation of NOX-Derived Reactive Oxygen Species in Cancer. Antioxidants, 12 (1). p. 67. ISSN 2076-3921
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Official URL: https://doi.org/10.3390/antiox12010067
Abstract
Activation of NADPH oxidases (NOX) and the ensuing formation of reactive oxygen species (ROS) is a vital aspect of antimicrobial defense but may also promote tumorigenesis. Enhanced NOX activity has been associated with aberrant activation of oncogenic cascades such as the phosphoinositide 3-kinase (PI3K) signaling pathway, which is upregulated in several malignancies. In this review, we examine the role of PI3K on the regulation of NOX-induced ROS formation in cancer.
| Item Type: | Article |
|---|---|
| Subjects: | European Repository > Agricultural and Food Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 15 Dec 2023 12:24 |
| Last Modified: | 15 Dec 2023 12:24 |
| URI: | http://go7publish.com/id/eprint/3968 |
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