Phytochemical Profiling and Antioxidant Activity of Aqueous Leaf Extract of Vitex negundo

Prakash, Palanisamy and Selvam, Kuppusamy and Umamaheswari, Govindarajan (2021) Phytochemical Profiling and Antioxidant Activity of Aqueous Leaf Extract of Vitex negundo. Journal of Pharmaceutical Research International, 33 (23B). pp. 22-32. ISSN 2456-9119

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Abstract

Natural products from plants, animals and minerals are the basis for treating human diseases. The present investigation explains that the antioxidant potential of aqueous extract of vitex negundo leaves. Phytochemical constituents, total phenolic and flavanoid content of aqueous analysis and vitro methods such as 1,1-diphenyl-2picrylhydrazyl (DPPH), 2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging assays and GC_MS studies are reported. In addition, TPC and TFC of the extract were evaluated. It was observed that the leaf extract total phenol (14.3 mg) and flavanoids (8.5 mg) Quercetin equivalent (Q/g) high level of Phenolic and flavonoid content that might have accounted for the strong activity observed ABTS 62% of inhibition µg/ mL almost equivalent to that of standard vitamin C and DPPH value of 66.32 µg/ mL almost equivalent to that of standard vitamin C results revealed that leaves of vitex negundo have Since this investigation is a preliminary study, a detailed study of the antioxidant mechanisms of specific phenol components is an absolute necessity. Many phytochemical constituents which may be responsible for many pharmacological activities.

Item Type: Article
Subjects: European Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 01 Apr 2023 04:31
Last Modified: 03 Jan 2024 06:18
URI: http://go7publish.com/id/eprint/435

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