Effect of chewing betel nut on the gut microbiota of Hainanese

Ying, Li and Yang, Yunjia and Zhou, Jun and Huang, Hairong and Du, Guankui and Pon Velayutham, Anandh Babu (2021) Effect of chewing betel nut on the gut microbiota of Hainanese. PLOS ONE, 16 (10). e0258489. ISSN 1932-6203

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Abstract

Betel nut chewing (BNC) is prevalent in South Asia and Southeast Asia. BNC can affect host health by modulating the gut microbiota. The aim of this study is to evaluate the effect of BNC on the gut microbiota of the host. Feces samples were obtained from 34 BNC individuals from Ledong and Lingshui, Hainan, China. The microbiota was analyzed by 16S rRNA gene sequencing. BNC decreased the microbial α-diversity. Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria were the predominant phyla, accounting for 99.35% of the BNC group. The Firmicutes-to-Bacteroidetes ratio was significantly increased in the BNC group compared to a control group. The abundances of the families Aerococcaceae, Neisseriaceae, Moraxellaceae, Porphyromonadaceae, and Planococcaceae were decreased in the BNC/BNC_Male/BNC_Female groups compared to the control group, whereas the abundances of Coriobacteriaceae, Streptococcaceae, Micrococcaceae, Xanthomonadaceae, Coxiellaceae, Nocardioidaceae, Rhodobacteraceae, and Succinivibrionaceae were increased. In general, the gut microbiome profiles suggest that BNC may have positive effects, such as an increase in the abundance of beneficial microbes and a reduction in the abundance of disease-related microbes. However, BNC may also produce an increase in the abundance of disease-related microbes. Therefore, extraction of prebiotic components could increase the beneficial value of betel nut.

Item Type: Article
Subjects: European Repository > Geological Science
Depositing User: Managing Editor
Date Deposited: 29 Mar 2023 04:06
Last Modified: 17 Jun 2024 05:43
URI: http://go7publish.com/id/eprint/832

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