Cryptogenic Stroke with a Patent Foramen Ovale in a Patient with Pulmonary Embolism and Thrombophilia: A Case-based Discussion

The patent foramen ovale (PFO) is a common abnormality that is often associated with cryptogenic stroke in young people. The management of PFO requires endovascular closure which prevents recurrence better than antithrombotic treatment. In the presence of concomitant thrombophilia, the risk of recurrence of stroke after closure of the PFO is increased, and one needs to institute antithrombotic therapy. The choice and duration of the treatment are controversial. Our study focuses on a 37-year-old patient admitted for ischemic vascular accident in whom a patent foramen ovale was found with an interatrial septal aneurysm (ASIA) on a ground of thrombophilia associated with a left pulmonary embolism and an occlusion. total left internal carotid artery.

Since at present, there is no optimal therapeutic strategy for these patients, the indications must be considered on an individual basis. The aim of the clinical case is to relate our experience in the management of cryptogenic stroke associated with PFO on a ground of thrombophilia.